Trisobbio is a comune in the Province of Alessandria in the Italian region Piedmont, located about 80 kilometres southeast of Turin and about 30 kilometres south of Alessandria. Trisobbio borders the following municipalities: Carpeneto, Cremolino, Montaldo Bormida, Morsasco, Orsara Bormida, Ovada, and Rocca Grimalda.
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