Masio is a comune in the Province of Alessandria in the Italian region Piedmont, located about 60 kilometres southeast of Turin and about 20 kilometres southwest of Alessandria. Masio borders the following municipalities: Cerro Tanaro, Cortiglione, Felizzano, Incisa Scapaccino, Oviglio, Quattordio, and Rocchetta Tanaro.
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